| Tissue Specificity |
Penicillins G, V, N, ampicillin, amoxicillin, hetacillin, cloxacillin, and other antibiotics with penicillanic acid core. Much higher affinity for hydrolyzed (open) beta-lactam ring than closed ring. Does not react with beta-lactams with cephalosporanic acid core, other classes of antibiotics, or milk and serum proteins. |