Rabbit Polyclonal antibody to PHOX2BThe DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq, Jul 2008]
Immunogen
PHOX2B antibody was raised against a 15 amino acid synthetic peptide near the center of human PHOX2B.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
WB: 1 - 2 ug/ml:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
NBLST2 NBPhox PMX2B paired-like homeobox 2b
Target
PHOX2B
Tissue Specificity
PHOX2B antibody is predicted to not cross-react with other paired homeobox family members.
Application
Application
Western blot analysis of PHOX2B in 293 cell lysate with PHOX2B antibody at (A) 1 and (B) 2 ug/mL.
Application Notes
WB: 1 - 2 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.