Mouse monoclonal antibody [3E5] to ALPPThere are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to human ALPP expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG2
Clone Number
3E5
Host Species
Mouse
Tested Applications
ELISAIHC-PWB
ELISA: 1/10000.
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
PLAP , PALP , ALP , PLAP-1
Target
ALPP
Molecular Weight(MW)
58 kDa (note)
Application
Application
Immunohistochemical analysis of paraffin-embedded ovarian cancer (A), stomach cancer (B) using ALPP mouse mAb with DAB staining
Application
Western blot analysis using ALPP mouse mAb against HepG2 (1), A431 (2) and MCF-7 (3) cell lysate.
Application Notes
ELISA: 1/10000.
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.