| Product Name | Placental Alkaline Phosphatase antibody [H7E8] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [H7E8] to PLAPThere are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The exact physiological function of the alkaline phosphatases is not known. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized. |
| Immunogen | Purified placental alkaline phosphatase |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | H7E8 |
| Host Species | Mouse |
| Tested Applications | ELISAIHC-FWB |
| ELISA: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 58 kDa. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | Alkaline phosphomonoesterase, ALPP, HGNC:439, Placental Alkaline Phosphatase, Alkaline phosphatase placental type1 precursor, Glycerophosphatase, Alkaline phosphatase placental type 1 precursor, Alkaline phosphatase placental type3 precursor, Alkaline phos |
|---|---|
| Target | PLAP |
| Application Notes | ELISA: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 58 kDa. Optimal dilutions/concentrations should be determined by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 0.09% sodium azide |
