| Product Name | Plectin antibody [7A8] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [7A8] to PlectinPlectin interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the crosslinking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics. |
| Immunogen | Plectin purified from rat glioma C6 cells. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 7A8 |
| Host Species | Mouse |
| Tested Applications | Dot,ELISA,ICC/IF,IHC-F,WB |
| Dot: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. ICC: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 300 kDa. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | Rat,Marsupials |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Pcn, Plec1, Pltn |
|---|---|
| Target | Plectin |
| Tissue Specificity | The antibody inhibits the interaction of plectin with vimentin and lamin B. |
| Positive Control | Tested with PtK2 cells |
|---|---|
| Application Notes | Dot: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. ICC: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 300 kDa. Optimal dilutions/concentrations should be determined by the end user. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.1% Sodium Azide; Constituents: Whole Serum |
