| Product Name | PR3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal to PR3 ( Proteinase 3 )Proteinase 3 (PR3), a constituent of azurophil granules of neutrophils (polymorphonuclear cells, PMNs), is the target antigen for most anti-neutrophil cytoplasmic antibodies (c-ANCA) in Wegener's Granulomatosis (WG). |
| Immunogen | HMC-1/PR3 Cell Granule Extract |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | MCPR3-2 |
| Host Species | Mouse |
| Tested Applications | ICC/IFWB |
| For IF: Use at a dilution of 1:10. For WB (non-reducing): Use at a dilution of 1:50-1:100 overnight at 4oC. Recommend using fresh lysate for best results. Optimal dilutions should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Target | PR3 |
|---|---|
| Light Chain Type | kappa |
| Positive Control | HMC-1/PR3-S176A Cells |
|---|---|
| Application Notes | For IF: Use at a dilution of 1:10. For WB (non-reducing): Use at a dilution of 1:50-1:100 overnight at 4oC. Recommend using fresh lysate for best results. Optimal dilutions should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM Phosphate-buffered saline, pH 7.4, containing 0.2% BSA and 0.1% sodium azide |
