Application
Antibody used in WB on Human brain at 0.2-1 ug/ml.Application
Antibody used in IHC on Mouse, Rat.| Product Name | ADAM15 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling.The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.1) Zhong, J.L., (2008) Mol. Cancer Res. 6 (3), 383-394. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ADAM15. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ADAM15 antibody can be used for detection of ADAM15 by ELISA at 1:62500. ADAM15 antibody can be used for detection of ADAM15 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ADAM15 |
|---|---|
| Alternative Names | ADAM15 MDC15 |
| Molecular Weight(MW) | 70 kDa |
Application
Antibody used in WB on Human brain at 0.2-1 ug/ml.
Application
Antibody used in IHC on Mouse, Rat.| Application Notes | ADAM15 antibody can be used for detection of ADAM15 by ELISA at 1:62500. ADAM15 antibody can be used for detection of ADAM15 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
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| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store ADAM15 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
