WB
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human liver cancer tissue, NIH/3T3 cells, Jurkat cells, Primary antibody: ADAM15 Antibod at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutesIHC
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using ADAM15 Antibody at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)IHC
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ADAM15 Antibody at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)| Product Name | Rabbit anti-ADAM15 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Fusion protein of Human ADAM15 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:200-1:1000 IHC:1:25-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ADAM15 |
|---|---|
| Gene Synonyms | MDC15 |
| Gene Full Name | ADAM metallopeptidase domain 15 |
| Gene Summary | The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| Alternative Names | A disintegrin and metalloproteinase domain 15 (metargidin) antibody A disintegrin and metalloproteinase domain 15 antibody ADA15_HUMAN antibody ADAM 15 antibody ADAM metallopeptidase domain 15 antibody Adam15 antibody and cysteine-rich protein 15 antibody Disintegrin and metalloproteinase domain-containing protein 15 antibody disintegrin-like antibody EC 3.4.24. antibody MDC 15 antibody MDC-15 antibody MDC15 antibody Metalloprotease RGD disintegrin protein antibody Metalloproteinase like disintegrin like and cysteine rich protein 15 antibody Metalloproteinase-like antibody Metargidin antibody |
| Cellular Localization | Endomembrane system; Single-pass type I membrane protein. Cell junction, adherens junction. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. |
WB
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human liver cancer tissue, NIH/3T3 cells, Jurkat cells, Primary antibody: ADAM15 Antibod at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
IHC
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using ADAM15 Antibody at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
IHC
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ADAM15 Antibody at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)| Application Notes | WB:1:200-1:1000 IHC:1:25-1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
