| Product Name | PRG2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [BMK-13] to PRG2The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | BMK-13 |
| Host Species | Mouse |
| Tested Applications | ELISAIHC-FIHC-P |
| Immunohistology - Frozen: 1/20 - 1/50: |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Gene Synonyms | MBP BMPG MBP1 |
|---|---|
| Target | Eosinophil Major Basic Protein |
| Tissue Specificity | Clone BMK-13 recongises the Eosinophil Major Basic Protein (EMBP, PRG2) and cross reacts weakly with basophils which also contain low levels of EMBP. No cross reactivity with other human cells or proteins has been noted. |
| Application Notes | Immunohistology - Frozen: 1/20 - 1/50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.02% Sodium Azide (NaN3) 0.1% Bovine Serum Albumin |
