Application
ICC/IF analysis of HeLa cells using PRMT6 antibody at a dilution of 1:300.Application
WB analysis of HeLa and 293T lysates using PRMT6 antibody at a dilution of 1:1,000.Application
IHC-P analysis of human breast cancer using PRMT6 antibody at a dilution of 1:200.| Product Name | PRMT6 antibody [2C3-F1-G1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [2C3-F1-G1] to PRMT6PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. IPRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication. |
| Immunogen | Purified recombinant human PRMT6 protein fragments expressed in E.coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2C3-F1-G1 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHCIHC-PWB |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | protein arginine methyltransferase 6 , HRMT1L6 |
|---|---|
| Target | PRMT6 |
| Molecular Weight(MW) | 42kDa (note) |
| Cellular Localization | Nucleus |
Application
ICC/IF analysis of HeLa cells using PRMT6 antibody at a dilution of 1:300.
Application
WB analysis of HeLa and 293T lysates using PRMT6 antibody at a dilution of 1:1,000.
Application
IHC-P analysis of human breast cancer using PRMT6 antibody at a dilution of 1:200.| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol |
