Application
Western blot analysis using PRMT6 mouse mAb against A431 (1), Hela (2), A549 (3) and HEK293 (4) cell lysate.| Product Name | PRMT6 antibody [4G2] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4G2] to PRMT6The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011] |
| Immunogen | The immunogen corresponding to human PRMT6 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4G2 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| ELISA: 1/10000. | |
| Species Reactivity | HumanMonkey |
| Concentration | 1mg/ml |
| Gene Synonyms | HRMT1L6 |
|---|---|
| Target | PRMT6 |
| Molecular Weight(MW) | 42 kDa (note) |
Application
Western blot analysis using PRMT6 mouse mAb against A431 (1), Hela (2), A549 (3) and HEK293 (4) cell lysate.| Application Notes | ELISA: 1/10000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
