| Product Name | proBNP antibody [18H5], N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [18H5] to pro-BNPThis gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Jul 2008] |
| Immunogen | Amino acids 13-27 of pro-BNP. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 18H5 |
| Host Species | Mouse |
| Tested Applications | ELISAIAWB |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BNP , NPPB |
|---|---|
| Target | BNP Prohormone |
| Tissue Specificity | This antibody detects pro-BNP. |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide (NaN3) |
