| Product Name | AKT3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AKT3, AKT3/PKBgamma, PRKBG, PKB gamma, Protein kinase Akt-3, RAC-gamma, MPPH, PKB-GAMMA, PKBG, Protein kinase B gamma, RAC-PK-gamma, STK-2 |
| Product description | Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activat phosphtidylinositol 3-kinase (PI 3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI-3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). Akt1, 2 and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for it activity. |
| Immunogen | AKT3 monoclonal antibody was raised against amino acids 119 - 136 of AKT3 (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WB |
| AKT3 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, immunofluorescence starting at 1:200 - 1:1000, and flow cytometry starting at 1:200 - 1:400.: |
|
| Species Reactivity | DogGorillaHorseHumanMonkeyMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | AKT3 |
|---|---|
| Alternative Names | AKT3 AKT3/PKBgamma PRKBG PKB gamma Protein kinase Akt-3 RAC-gamma MPPH PKB-GAMMA PKBG Protein kinase B gamma RAC-PK-gamma STK-2 |
| Application Notes | AKT3 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, immunofluorescence starting at 1:200 - 1:1000, and flow cytometry starting at 1:200 - 1:400.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store AKT3 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.05% BSA, 0.05% sodium azide. |
