Application
Western blot analysis of anti-ALOX5AP Antibody in K562 cell line lysates (35ug/lane).Application
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.| Product Name | ALOX5AP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein, ALOX5AP, FLAP |
| Product description | ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.1) Zintzaras,E., Am. J. Epidemiol. 169 (5), 523-532 (2009) |
| Immunogen | This ALOX5AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from the Central region of human ALOX5AP. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | ALOX5AP |
|---|---|
| Alternative Names | Arachidonate 5-lipoxygenase-activating protein FLAP MK-886-binding protein ALOX5AP FLAP |
| Molecular Weight(MW) | 18 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine |
Application
Western blot analysis of anti-ALOX5AP Antibody in K562 cell line lysates (35ug/lane).
Application
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
