Application
Western blot analysis of ALSFTD in HeLa cell lysate with ALSFTD antibody at 1 μg/ml.Application
Immunocytochemistry of ALSFTD in A-20 cells with ALSFTD antibody at 10 μg/ml.| Product Name | ALSFTD Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Amyotrophic lateral sclerosis with frontotemporal dementia, chromosome 9 open reading frame 72, C9orf72 |
| Product description | ALSFTD (C9orf72) is considered to play a role in gender determination (1). Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2). Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3,4).1) Takada LT and Sha SJ. Neuropsychiatric features of C9orf72-associated behavioral variant frontotemporal dementia and frontotemporal dementia with motor neuron disease. Alzheimers Res. Ther. 2012; 4:38. |
| Immunogen | ALSFTD antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ALSFTD. The immunogen is located within amino acids 400 - 450 of ALSFTD. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| ALSFTD antibody can be used for the detection of ALSFTD by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry at 10 μg/ml.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ALSFTD |
|---|---|
| Alternative Names | Amyotrophic lateral sclerosis with frontotemporal dementia chromosome 9 open reading frame 72 C9orf72 |
| Molecular Weight(MW) | Predicted: 53 kDa Observed: 52 kDa |
| Sequence Similarities | 2) Cat. No. 17-208 - A-20 Cell Slide |
| Tissue Specificity | ALSFTD antibody is human, mouse and rat reactive. At least two isoforms are known to exist. |
Application
Western blot analysis of ALSFTD in HeLa cell lysate with ALSFTD antibody at 1 μg/ml.
Application
Immunocytochemistry of ALSFTD in A-20 cells with ALSFTD antibody at 10 μg/ml.| Positive Control | 1) Cat. No. 1288 - A20 Cell Lysate |
|---|---|
| Application Notes | ALSFTD antibody can be used for the detection of ALSFTD by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry at 10 μg/ml.: |
| Form | Liquid |
|---|---|
| Storage Instructions | ALSFTD antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | ALSFTD Antibody is supplied in PBS containing 0.02% sodium azide. |
