Application
Western blot analysis of APRIL expression in Jurkat cells with APRIL antibody at 1 μg/mL (A), 2 μg/mL (B), and 4 μg/mL (C).Application
Immunohistochemistry of APRIL in human prostate tissue with APRIL antibody at 10 μg/mL.| Product Name | APRIL Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APRIL Antibody: APRIL, CD256, TALL2, ZTNF2, TALL-2, TRDL-1, UNQ383/PRO715, APRIL, Tumor necrosis factor ligand superfamily member 13, A proliferation-inducing ligand |
| Product description | APRIL Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1α (for TNF related death ligand 1α) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.1) Hahne M, Kataoka T, Schroter M, et al. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. J. Exp. Med. 1998; 188:1185-90. |
| Immunogen | APRIL antibody was raised against a synthetic peptide corresponding to amino acids within a extracellular domain of human APRIL. The immunogen is located within amino acids 180 - 230 of APRIL. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| APRIL antibody can be used for detection of APRIL by Western blot at 1 - 4 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TNFSF13 |
|---|---|
| Alternative Names | APRIL Antibody: APRIL CD256 TALL2 ZTNF2 TALL-2 TRDL-1 UNQ383/PRO715 APRIL Tumor necrosis factor ligand superfamily member 13 A proliferation-inducing ligand |
| Molecular Weight(MW) | Predicted: 27 kDa Observed: 27 kDa |
| Sequence Similarities | 2) Cat. No. 1312 - Human Prostate Tissue Lysate |
Application
Western blot analysis of APRIL expression in Jurkat cells with APRIL antibody at 1 μg/mL (A), 2 μg/mL (B), and 4 μg/mL (C).
Application
Immunohistochemistry of APRIL in human prostate tissue with APRIL antibody at 10 μg/mL.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | APRIL antibody can be used for detection of APRIL by Western blot at 1 - 4 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | APRIL antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | APRIL Antibody is supplied in PBS containing 0.02% sodium azide. |
