Application
Antibody used in WB on Human Fetal Muscle at 1 ug/ml.| Product Name | AREB6 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AREB6, AREB6, BZP, MGC133261, NIL-2-A, NIL-2A, TCF8, ZEB, ZFHEP, ZFHX1A, FECD6, NIL2A, PPCD3, DELTAEF1 |
| Product description | Transcription Factor AREB6 / transcription factor 8 /zinc finger homeodomain enhancer-binding protein inhibits interleukin-2 (IL-2) gene expression. May be responsible for transcriptional repression of the IL-2 gene. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type.ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).1) Gregory, P.A., (2008) Nat. Cell Biol. 10 (5), 593-601. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AREB6. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| AREB6 antibody can be used for detection of AREB6 by ELISA at 1:12500. AREB6 antibody can be used for detection of AREB6 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ZEB1 |
|---|---|
| Alternative Names | AREB6 AREB6 BZP MGC133261 NIL-2-A NIL-2A TCF8 ZEB ZFHEP ZFHX1A FECD6 NIL2A PPCD3 DELTAEF1 |
| Molecular Weight(MW) | 124 kDa |
Application
Antibody used in WB on Human Fetal Muscle at 1 ug/ml.| Positive Control | 1) Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate |
|---|---|
| Application Notes | AREB6 antibody can be used for detection of AREB6 by ELISA at 1:12500. AREB6 antibody can be used for detection of AREB6 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store AREB6 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
