Application
Immunohistochemistry of ATAD3B in human kidney tissue with ATAD3B antibody at 5 μg/mL.Application
Western blot analysis of ATAD3B in human kidney tissue lysate with ATAD3B antibody at (A) 1 and (B) 2 μg/mL .| Product Name | ATAD3B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ATAD3B Antibody: TOB3, AAA-TOB3, KIAA1273, TOB3, ATPase family AAA domain-containing protein 3B |
| Product description | ATAD3B Antibody: ATAD3B is a member of the AAA ATPase family, a family of proteins that catalyze ATP into ADP and are involved in several cellular functions such as cell-cycle regulation, protein proteolysis and transport. The AAA ATPase family is characterized by a highly conserved AAA motif containing Walker homology sequences and imparting ATPase activity. Mitochondrial membrane proteins ATAD3A/B contribute to the stabilization of nucleoids and may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The gene encoding ATAD3A/B/C maps to human chromosome 1 and has been suggested to be an anti-apoptotic marker.1) Patel S and Latterich M. The AAA team: related ATPases with diverse functions. Trends Cell Biol. 1998; 8:65-71. |
| Immunogen | ATAD3B antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human ATAD3B. The immunogen is located within amino acids 570 - 620 of ATAD3B. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| ATAD3B antibody can be used for detection of ATAD3B by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ATAD3B |
|---|---|
| Alternative Names | ATAD3B Antibody: TOB3 AAA-TOB3 KIAA1273 TOB3 ATPase family AAA domain-containing protein 3B |
| Sequence Similarities | 2) Cat. No. 10-401 - Human Kidney Tissue Slide |
| Tissue Specificity | ATAD3B antibody is predicted to not cross-react with other ATAD protein family members. At least three isoforms of ATAD3B are known to exist. |
Application
Immunohistochemistry of ATAD3B in human kidney tissue with ATAD3B antibody at 5 μg/mL.
Application
Western blot analysis of ATAD3B in human kidney tissue lysate with ATAD3B antibody at (A) 1 and (B) 2 μg/mL .| Positive Control | 1) Cat. No. 1305 - Human Kidney Tissue Lysate |
|---|---|
| Application Notes | ATAD3B antibody can be used for detection of ATAD3B by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | ATAD3B antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ATAD3B Antibody is supplied in PBS containing 0.02% sodium azide. |
Data sheet for OM271787