Application
Western blot analysis in K562 cell line lysates (35ug/lane).| Product Name | ATP2A2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, ATP2A2, ATP2B |
| Product description | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) |
| Immunogen | This ATP2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the Central region of human ATP2A2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ATP2A2 |
|---|---|
| Alternative Names | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 SERCA2 SR Ca(2+)-ATPase 2 Calcium pump 2 Calcium-transporting ATPase sarcoplasmic reticulum type slow twitch skeletal muscle isoform Endoplasmic reticulum class 1/2 Ca(2+) ATPase ATP2A2 ATP2B |
| Molecular Weight(MW) | 115 kDa |
Application
Western blot analysis in K562 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
