Application
staining PSCA in human breast carcinoma by Immunohistochemistry (FFPE-sections)Application
Human Prostate Carcinoma stained with anti-Prostate Stem Cell Antigen (PSCA) antibody| Product Name | PSCA antibody (ready-to-use) |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to PSCA predilutedPSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer. |
| Immunogen | Synthetic peptide (Human) (extracellular). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 8000 PRO232 O43653 602470 PSCA |
|---|---|
| Target | PSCA |
| Cellular Localization | Plasma membrane |
Application
staining PSCA in human breast carcinoma by Immunohistochemistry (FFPE-sections)
Application
Human Prostate Carcinoma stained with anti-Prostate Stem Cell Antigen (PSCA) antibody| Positive Control | Bladder carcinoma and Prostate carcinoma |
|---|---|
| Application Notes | IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution and store at 4°C. Do not freeze. |
| Storage Buffer | PBS, pH 7.4 containing 1%BSA and 0.1% sodium azide |
