Application
PSD95 visualized using tested on Bouin's fixed paraffin-embedded backskin sections of transgenic mice- basal, hair follicle and dermal staining.Application
ICC localization of Psd95 in rat neocortex.Application
Western blot analysis of PSD95 in rat membrane using a 1:1000 dilution of| Product Name | PSD95 antibody [7E3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [7E3] to PSD95Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. |
| Immunogen | Recombinant rat PSD-95 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 7E3 |
| Host Species | Mouse |
| Tested Applications | ICC/IFWB |
| We recommend a working dilution of 1µg/ml was sufficient for detection of PSD-95 on 20µg rat brain tissue extract.. | |
| Species Reactivity | MouseRatBovine |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein G |
| Gene Synonyms | SAP90, DLG4, Dlgh4, PSD95 |
|---|---|
| Target | PSD95 |
| Molecular Weight(MW) | 100kDa (note) |
| Cellular Localization | Membrane-associated. High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells. |
Application
PSD95 visualized using tested on Bouin's fixed paraffin-embedded backskin sections of transgenic mice- basal, hair follicle and dermal staining.
Application
ICC localization of Psd95 in rat neocortex.
Application
Western blot analysis of PSD95 in rat membrane using a 1:1000 dilution of| Application Notes | We recommend a working dilution of 1µg/ml was sufficient for detection of PSD-95 on 20µg rat brain tissue extract.. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS pH7.4, 50% glycerol |
