Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.1) Fukazawa H, et al. (2004) Mol Cancer Ther ; 3 (10): 1281-1288Luciano F, et al. (2003) Oncogene ; 22 (43): 6785-6793
Immunogen
BIM (Ab-69) antibody was raised against a peptide sequence around aa.67~71 (P-A-S-P-G) derived from Human BIM.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHCWB
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100