Butyrophilin subfamily 3 member A1, CD277, BTN3A1, BTF5
Product description
The butyrophilin (BTN) genes are a group of major
histocompatibility complex (MHC)-associated genes that encode type
I membrane proteins with 2 extracellular immunoglobulin (Ig)
domains and an intracellular B30.2 (PRYSPRY) domain. Three
subfamilies of human BTN genes are located in the MHC class I
region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2
(e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which
have undergone tandem duplication, resulting in 3 copies of each
(summary by Smith et al., 2010 [PubMed 20208008]).[supplied by
OMIM].1) Smith, I.A., et al. J. Immunol. 184(7):3514-3525(2010)
Immunogen
This BTN3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the C-terminal region of human BTN3A1.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.