Application
Antibody used in IHC on Human placental at 1:50.Application
Antibody used in WB on Human placenta at: 1:500 (Lane1: 50 ug human placental tissue lysate, Lane2: 40 ug human placental tissue lysate, Lane3: 30 ug human placental tissue lysate, Lane4: 20 ug human placental tissue lysate, Lane5: 20 ug human myometrial tissue lysate).Application
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.| Product Name | CAV3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.1) Alias, L., et al., (2004) Neuromuscul. Disord. 14 (5), 321-324. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CAV3. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISA,WB |
| CAV3 antibody can be used for detection of CAV3 by ELISA at 1:12500. CAV3 antibody can be used for detection of CAV3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Dog,Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CAV3 |
|---|---|
| Alternative Names | CAV3 LQT9 VIP21 LGMD1C VIP-21 |
| Molecular Weight(MW) | 17 kDa |
Application
Antibody used in IHC on Human placental at 1:50.
Application
Antibody used in WB on Human placenta at: 1:500 (Lane1: 50 ug human placental tissue lysate, Lane2: 40 ug human placental tissue lysate, Lane3: 30 ug human placental tissue lysate, Lane4: 20 ug human placental tissue lysate, Lane5: 20 ug human myometrial tissue lysate).
Application
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.| Application Notes | CAV3 antibody can be used for detection of CAV3 by ELISA at 1:12500. CAV3 antibody can be used for detection of CAV3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CAV3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
