The protein encoded by this gene is a member of the beta
chemokine receptor family. It is predicted to be a seven
transmembrane protein similar to G protein-coupled receptors.
Chemokines and their receptors are key regulators of the thymocytes
migration and maturation in normal and inflammation conditions. The
specific ligand of this receptor is CCL25. It has been found that
this gene is differentially expressed by T lymphocytes of small
intestine and colon, suggested a role in the thymocytes recruitment
and development that may permit functional specialization of immune
responses in different segment of the gastrointestinal tract. This
gene is mapped to the chemokine receptor gene cluster region. Two
alternatively spliced transcript variants have been described.1) Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Immunogen
This CCR9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-334 amino acids from the C-terminal region of human CCR9.
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.