Rabbit Polyclonal antibody to PTP4A3Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
Immunogen
Peptide sequence around aa. 161-166 (K-D-P-H-T) derived from Human PTP4A3.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity
HumanMouse
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
PRL-3 PRL-R PRL3 PTP4A3 protein-tyrosine phosphatase 4a3 protein tyrosine phosphatase type IVA 3 protein-tyrosine phosphatase of regenerating liver 3 potentially prenylated protein tyrosine phosphatase protein tyrosine phosphatase type IVA member
Target
PTP4A3
Molecular Weight(MW)
22 (note)
Application
Application
Western blot analysis of extract from LX-2 cells transfected with PRL-3 using PRL-3 antibody .
Application Notes
Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.