| Product description |
The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, and macrophages. In the mouse as opposed to the human, CD38 expression is downregulated on mouse germinal center B cells and plasma cells. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.1) Gonzlez-lvaro, I., Domnguez-Jimnez, C., Ortiz, A. M., Nez-Gonzlez, V., Roda-Navarro, P., Fernndez-Ruiz, E., ... Snchez-Madrid, F. (2006). Interleukin-15 and interferon- gammaparticipate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production.Arthritis research therapy,8(4), R88. |