| Product Name | CD64 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD64, FCRI, CD64A, IGFR1, FCGR1A |
| Product description | The 10.1 monoclonal antibody specifically reacts with human CD64, a 75kDA type I transmembrane glycoprotein that is the high affinity receptor for IgG. CD64 is expressed on macrophages and dendritic cells and is involved in antibody-dependent cellular toxicity, cytokine release phagocytosis, and endocytosis. The 10.1 antibody is reported to recognize the EC3 epitope of CD64.1) Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | FACSFunctionalStudiesIHC |
| FACS:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FCGR1A |
|---|---|
| Alternative Names | CD64 FCRI CD64A IGFR1 FCGR1A |
| Tissue Specificity | The 15.2 antibody reacts with the 85-110 kDa intracellular adhesion molecule-1 (ICAM-1), a member of the Ig superfamily which acts as a ligand for the Lymphocyte Function-Associated Antigen-1 (LFA-1). |
| Entrez Gene | 2209 |
|---|
| Application Notes | FACS:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The product should be stored undiluted at 4˚C . Do not freeze. |
| Storage Buffer | Phosphate-buffered aqueous solution, ph7.2. |
