| Product Name | CD95 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, FAS |
| Product description | The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. It is expressed on fibroblasts, monocytes, lymphocytes, and neutrophils. CD95 induces apoptosis after binding with CD178 or Fas ligand and the EOS9.1 antibody is reported to be used for inducing apoptosis in Fas-positive cells.1) Deaglio, S., Zubiaur, M., Gregorini, A., Bottarel, F., Ausiello, C. M., Dianzani, U., ... Malavasi, F. (2002). Human CD38 and CD16 are functionally dependent and physically associated in natural killer cells.Blood,99(7), 2490-2498. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM,k |
| Host Species | Mouse |
| Tested Applications | FACSFunctionalStudies |
| FACS:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FAS |
|---|---|
| Alternative Names | APT1 CD95 FAS1 APO-1 FASTM ALPS1A TNFRSF6 FAS |
| Tissue Specificity | The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. |
| Entrez Gene | 355 |
|---|
| Application Notes | FACS:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The product should be stored undiluted at 4˚C . Do not freeze. |
| Storage Buffer | Phosphate-buffered aqueous solution, ph7.2. |
Data sheet for OM275015