Application
Western blot analysis of anti-CLASP2 Antibody in mouse kidney tissue lysates (35ug/lane).Application
Formalin-fixed and paraffin-embedded human Hepatocellular carcinoma reacted with anti-CLASP2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.| Product Name | CLASP2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, Protein Orbit homolog 2, hOrbit2, CLASP2, KIAA0627 |
| Product description | Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.1) Pereira,A.L., Mol. Biol. Cell 17 (10), 4526-4542 (2006) |
| Immunogen | This CLASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-975 amino acids from the C-terminal region of human CLASP2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CLASP2 |
|---|---|
| Alternative Names | CLIP-associating protein 2 Cytoplasmic linker-associated protein 2 Protein Orbit homolog 2 hOrbit2 CLASP2 KIAA0627 |
| Molecular Weight(MW) | 141 kDa |
Application
Western blot analysis of anti-CLASP2 Antibody in mouse kidney tissue lysates (35ug/lane).
Application
Formalin-fixed and paraffin-embedded human Hepatocellular carcinoma reacted with anti-CLASP2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
