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CLOCK Antibody

Catalog Number:OM275703
OM275703
Discount Price
OM275703-100ul
1~2 Week
100ul
OM275703-50ul
50ul
OM275703-20ul
20ul
1~2 Week
Product Profile
Product Name CLOCK Antibody
Antibody Type Primary Antibodies
Antigen Alias Circadian locomoter output cycles protein kaput, hCLOCK, Class E basic helix-loop-helix protein 8, bHLHe8, CLOCK, BHLHE8, KIAA0334
Product description CLOCK belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within this protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.1) Sookoian,S., Am. J. Clin. Nutr. 87 (6), 1606-1615 (2008)
Immunogen This CLOCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-249 amino acids from the Central region of human CLOCK.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Symbol CLOCK
Alternative Names Circadian locomoter output cycles protein kaput
hCLOCK
Class E basic helix-loop-helix protein 8
bHLHe8
CLOCK
BHLHE8
KIAA0334
Molecular Weight(MW) 95 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Mouse
Database Links
Entrez Gene 9575
Protein Accession O15516
Application

Application

Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with CLOCK antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Application

Western blot analysis of CLOCK Antibody in NCI-H460 cell line lysates (35ug/lane)
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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