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COPS2 Antibody

Catalog Number:OM275939
OM275939
Discount Price
OM275939-100ul
1~2 Week
100ul
OM275939-50ul
50ul
OM275939-20ul
20ul
1~2 Week
Product Profile
Product Name COPS2 Antibody
Antibody Type Primary Antibodies
Antigen Alias COPS2, ALIEN, CSN2, SGN2, TRIP15
Product description COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.1) Moehren, U., (2004) (er) Nucleic Acids Res. 32 (10), 2995-3004.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COPS2.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAIHCWB
COPS2 antibody can be used for detection of COPS2 by ELISA at 1:312500. COPS2 antibody can be used for detection of COPS2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity DogHumanMouseRatZebra Fish
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol COPS2
Alternative Names COPS2
ALIEN
CSN2
SGN2
TRIP15
Molecular Weight(MW) 51 kDa
Database Links
Entrez Gene 9318
Protein Accession NP_004227
Application

Application

Antibody used in WB on Human HEK293T cells at 2.5 ug/ml.

Application

Antibody used in IHC on Human Skin.
Positive Control 1) Tranfected 293T Cell Lysate
Application Notes COPS2 antibody can be used for detection of COPS2 by ELISA at 1:312500. COPS2 antibody can be used for detection of COPS2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store COPS2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
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