Cytochrome c oxidase subunit 5A, mitochondrial, Cytochrome c oxidase polypeptide Va, COX5A
Product description
Cytochrome c oxidase (COX) is the terminal enzyme of the
mitochondrial respiratory chain. It is a multi-subunit enzyme
complex that couples the transfer of electrons from cytochrome c to
molecular oxygen and contributes to a proton electrochemical
gradient across the inner mitochondrial membrane. The complex
consists of 13 mitochondrial- and nuclear-encoded subunits. The
mitochondrially-encoded subunits perform the electron transfer of
proton pumping activities. The functions of the nuclear-encoded
subunits are unknown but they may play a role in the regulation and
assembly of the complex. This gene encodes the nuclear-encoded
subunit Va of the human mitochondrial respiratory chain enzyme. A
pseudogene COX5AP1 has been found in chromosome 14q22. [provided by
RefSeq].1) Chen, Z.X., et al. Cell Death Differ. 17(3):408-420(2010)
Immunogen
This COX5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human COX5A.
Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.