Cleavage and polyadenylation specificity factor subunit 6, Cleavage and polyadenylation specificity factor 68 kDa subunit, CFIm68, CPSF 68 kDa subunit, Pre-mRNA cleavage factor Im 68 kDa subunit, Protein HPBRII-4/7, CPSF6, CFIM68
Product description
The protein encoded by this gene is one subunit of a
cleavage factor required for 3' RNA cleavage and polyadenylation
processing. The interaction of the protein with the RNA is one of
the earliest steps in the assembly of the 3' end processing complex
and facilitates the recruitment of other processing factors. The
cleavage factor complex is composed of four polypeptides. This gene
encodes the 68kD subunit. It has a domain organization reminiscent
of spliceosomal proteins.1) Lee, K., et al. Cell Host Microbe 7(3):221-233(2010)
Immunogen
This CPSF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human CPSF6.
Western Blot at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 ug per lane.
Application
Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.