CREBZF belongs to the bZIP family. It strongly activates transcription when bound to HCFC1. The protein suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. It also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. CREBZF is able to down-regulate expression of some cellular genes in CREBZF-expressing cells.1) Misra, V., (2005) J. Biol. Chem. 280 (15), 15257-15266.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREBZF.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
CREBZF antibody can be used for detection of CREBZF by ELISA at 1:1562500. CREBZF antibody can be used for detection of CREBZF by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
CREBZF antibody can be used for detection of CREBZF by ELISA at 1:1562500. CREBZF antibody can be used for detection of CREBZF by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CREBZF antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.