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CTNND2 Antibody

Catalog Number:OM276351
OM276351
Discount Price
OM276351-100ul
1~2 Week
100ul
OM276351-50ul
50ul
OM276351-20ul
20ul
1~2 Week
Product Profile
Product Name CTNND2 Antibody
Antibody Type Primary Antibodies
Product description This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen This CTNND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1131-1159 amino acids from the C-terminal region of human CTNND2.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CTNND2
Alternative Names Catenin delta-2
Delta-catenin
GT24
Neural plakophilin-related ARM-repeat protein
NPRAP
Neurojungin
CTNND2
NPRAP
Molecular Weight(MW) 133 kDa
Database Links
Entrez Gene 1501
Protein Accession Q9UQB3
Application

Application

CTNND2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western blot analysis in mouse lung tissue lysates (35ug/lane).

Application

Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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