CX3CR1 a Chemokine Receptor is an HIV coreceptor, as well as a leukocyte chemotactic/adhesion receptor for fractalkine, also known as neurotactin. CX3CR1 mediates chemotactic responses to the soluble form of fractalkine in neutrophils and T cells, and cytoadhesion to cells expressing membrane-anchored fractalkine, such as monocytes, T cells, and neutrophils. Cells transfected with CX3CR1 exhibited chemotaxis and transient increases in intracellular calcium concentration when exposed to fractalkine.
Immunogen
CX3CR1 antibody was raised against a peptide located in the 3rd extracellular domain of CX3CR1 (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHC
CX3CR1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.: