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DCLRE1B Antibody

Catalog Number:OM276793
OM249509 WB.jpg" data-gallery-id="gallery2" data-title="WB" data-description="RT-qPCR (A, B) and western blot (C, D) were used to measure DCLRE1B and HOMER1 expressions." data-app="WB" alt="WB" onerror="this.src='//www.omnimabs.com/content/xtheme/oumeini/images/noimage.jpg'">
OM276793
Discount Price
OM276793-100ul
1~2 Week
100ul
OM276793-50ul
50ul
OM276793-20ul
20ul
1~2 Week
Product Profile
Product Name DCLRE1B Antibody
Antibody Type Primary Antibodies
Product description

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).1) Anders, M., et al. Cell Cycle 8(11):1725-1732(2009) Liu, L., et al. Cell Cycle 8(4):628-638(2009) Freibaum, B.D., et al. J. Biol. Chem. 283(35):23671-23676(2008) Bae, J.B., et al. Oncogene 27(37):5045-5056(2008) Demuth, I., et al. DNA Repair (Amst.) 7(8):1192-1201(2008) Matsuoka, S., et al. Science 316(5828):1160-1166(2007) Lenain, C., et al. Curr. Biol. 16(13):1303-1310(2006) Freibaum, B.D., et al. J. Biol. Chem. 281(22):15033-15036(2006) Ishiai, M., et al. Mol. Cell. Biol. 24(24):10733-10741(2004) Demuth, I., et al. Oncogene 23(53):8611-8618(2004) Dronkert, M.L., et al. Mol. Cell. Biol. 20(13):4553-4561(2000)

Immunogen This DCLRE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-236 amino acids from the Central region of human DCLRE1B.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol DCLRE1B
Alternative Names 5' exonuclease Apollo
31--
DNA cross-link repair 1B protein
SNM1 homolog B
SNMIB
hSNM1B
DCLRE1B
SNM1B
Molecular Weight(MW) 60 kDa
Database Links
Entrez Gene 64858
Protein Accession Q9H816
Application

Application

DCLRE1B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the detected DCLRE1B protein (arrow).
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WB

RT-qPCR (A, B) and western blot (C, D) were used to measure DCLRE1B and HOMER1 expressions.
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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