Application
Immunofluorescence of DDX41 in rat brain tissue with DDX41 antibody at 20 μg/ml.Application
Immunohistochemistry of DDX41 in rat brain tissue with DDX41 antibody at 2.5 μg/ml.Application
Western blot analysis of DDX41 in rat brain tissue lysate with DDX41 antibody at 1 μg/mL.| Product Name | DDX41 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DDX41 Antibody: ABS, ABS, Probable ATP-dependent RNA helicase DDX41, DEAD box protein 41 |
| Product description | DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.1) Cordin O, Banroques J, Tanner NK, et al. The DEAD-box protein family of RNA helicases. Gene 2006; 367:17-37. |
| Immunogen | DDX41 antibody was raised against a 17 amino acid peptide near the amino terminus of human DDX41. The immunogen is located within amino acids 230 - 280 of DDX41. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| DDX41 antibody can be used for detection of DDX41 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DDX41 |
|---|---|
| Alternative Names | DDX41 Antibody: ABS ABS Probable ATP-dependent RNA helicase DDX41 DEAD box protein 41 |
| Molecular Weight(MW) | Predicted: 68 kDa Observed: 70 kDa |
| Tissue Specificity | At least two isoforms of DDX41 are known to exist; this antibody will detect both isoforms. |
Application
Immunofluorescence of DDX41 in rat brain tissue with DDX41 antibody at 20 μg/ml.
Application
Immunohistochemistry of DDX41 in rat brain tissue with DDX41 antibody at 2.5 μg/ml.
Application
Western blot analysis of DDX41 in rat brain tissue lysate with DDX41 antibody at 1 μg/mL.| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | DDX41 antibody can be used for detection of DDX41 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | DDX41 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | DDX41 Antibody is supplied in PBS containing 0.02% sodium azide. |
