Diphthamide biosynthesis protein 2, DPH2 homolog, HsDph2, Diphthamide biosynthesis protein 2 homolog-like 2, DPH2-like 2, DPH2, DPH2L2
Product description
This gene is one of two human genes similar to the yeast
gene dph2. The yeast gene was identified by its ability to
complement a diphthamide mutant strain, and thus probably functions
in diphthamide biosynthesis. Diphthamide is a post-translationally
modified histidine residue present in elongation factor 2 (EF2)
that is the target of diphtheria toxin ADP-ribosylation. Two
transcript variants encoding different isoforms have been found for
this gene.1) Rose, J. Phd, et al. Mol. Med. (2010) In press :
Immunogen
This DPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-148 amino acids from the N-terminal region of human DPH2.
Western blot analysis in CEM cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.