Application
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.| Product Name | DSC3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DSC3, CDHF3, DSC, DSC1, DSC2, DSC4, HT-CP |
| Product description | DSC3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.1) Wang, L., (2007) Virchows Arch. 451 (5), 959-966. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DSC3. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| DSC3 antibody can be used for detection of DSC3 by ELISA at 1:62500. DSC3 antibody can be used for detection of DSC3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DSC3 |
|---|---|
| Alternative Names | DSC3 CDHF3 DSC DSC1 DSC2 DSC4 HT-CP |
| Molecular Weight(MW) | 85 kDa |
Application
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | DSC3 antibody can be used for detection of DSC3 by ELISA at 1:62500. DSC3 antibody can be used for detection of DSC3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store DSC3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
