Application
Western blot analysis of lysate from A431 cell line, using DSC3 Antibody at 1:1000 at each lane.| Product Name | DSC3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Desmocollin-3, Cadherin family member 3, Desmocollin-4, HT-CP, DSC3, CDHF3, DSC4 |
| Product description | The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : |
| Immunogen | This DSC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 822-850 amino acids from the C-terminal region of human DSC3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DSC3 |
|---|---|
| Alternative Names | Desmocollin-3 Cadherin family member 3 Desmocollin-4 HT-CP DSC3 CDHF3 DSC4 |
| Molecular Weight(MW) | 100 kDa |
Application
Western blot analysis of lysate from A431 cell line, using DSC3 Antibody at 1:1000 at each lane.| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
