Application
Antibody used in IHC on Human Colon at 5.0 ug/ml.Application
Antibody used in WB on Human HeLa at 1 ug/ml.| Product Name | DSG2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DSG2, ARVC10, ARVD10, CDHF5, HDGC, MGC117034, MGC117036, MGC117037, CMD1BB |
| Product description | Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. DSG2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Cirillo, N., (2008) J. Cell. Biochem. 103 (2), 598-606. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DSG2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| DSG2 antibody can be used for detection of DSG2 by ELISA at 1:1562500. DSG2 antibody can be used for detection of DSG2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DSG2 |
|---|---|
| Alternative Names | DSG2 ARVC10 ARVD10 CDHF5 HDGC MGC117034 MGC117036 MGC117037 CMD1BB |
| Molecular Weight(MW) | 114 kDa |
Application
Antibody used in IHC on Human Colon at 5.0 ug/ml.
Application
Antibody used in WB on Human HeLa at 1 ug/ml.| Positive Control | 1) Cat. No. 1201 - HeLa Cell Lysate |
|---|---|
| Application Notes | DSG2 antibody can be used for detection of DSG2 by ELISA at 1:1562500. DSG2 antibody can be used for detection of DSG2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store DSG2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
