Application
Immunohistochemistry of EMX2 in human prostate tissue with EMX2 antibody at 5 μg/mL.| Product Name | EMX2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EMX2 Antibody: Homeobox protein EMX2, Empty spiracles homolog 2 |
| Product description | EMX2 Antibody: EMX2, like its closely related homolog EMX1, is a homeobox transcription factor involved in specifying cell fates in the developing central nervous system and participates in the development of olfactory neurons. EMX2 is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10.1) Bishop KM, Garel S, Nakagawa Y, et al. EMX1 and Emx2 cooperate to regulate cortical size, lamination, neuronal differentiation, development of cortical efferents, and thalamocortical pathfinding. J. Comp. Neurol. 2003; 457:345-60. |
| Immunogen | EMX2 antibody was raised against an 16 amino acid synthetic peptide near the amino terminus of human EMX2. The immunogen is located within the first 50 amino acids of EMX2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-P |
| EMX2 antibody can be used for detection of EMX2 by immunohistochemistry at 5 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | EMX2 |
|---|---|
| Alternative Names | EMX2 Antibody: Homeobox protein EMX2 Empty spiracles homolog 2 |
| Molecular Weight(MW) | 28 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Mouse: (94%) |
| Tissue Specificity | At least two isoforms of EMX2 are known to exist; this antibody will detect both isoforms. EMX2 antibody is predicted to not cross-react with EMX1. |
Application
Immunohistochemistry of EMX2 in human prostate tissue with EMX2 antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 10-635 - Human Prostate Tissue Slide |
|---|---|
| Application Notes | EMX2 antibody can be used for detection of EMX2 by immunohistochemistry at 5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | EMX2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | EMX2 Antibody is supplied in PBS containing 0.02% sodium azide. |
