Application
Western blot analysis in U251 cell line lysates (35ug/lane).| Product Name | EXOSC4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A, EXOSC4, RRP41, SKI6 |
| Product description | Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. Required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity. Plays a role in replication-dependent histone mRNA degradation.1) Mullen, T.E., et al. Genes Dev. 22(1):50-65(2008) |
| Immunogen | This EXOSC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-96 amino acids from the Central region of human EXOSC4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | EXOSC4 |
|---|---|
| Alternative Names | Exosome complex component RRP41 Exosome component 4 Ribosomal RNA-processing protein 41 p12A EXOSC4 RRP41 SKI6 |
| Molecular Weight(MW) | 26 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine |
Application
Western blot analysis in U251 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
