EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3'-5' exonuclease activity.1) Oh, J.H., (2005) Mamm. Genome 16 (12), 942-954.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EXOSC4.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHCWB
EXOSC4 antibody can be used for detection of EXOSC4 by ELISA at 1:62500. EXOSC4 antibody can be used for detection of EXOSC4 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Antibody used in IHC on Human Heart at 4.0-8.0 ug/ml.
Application
Antibody used in IHC on Human Liver at 4.0-8.0 ug/ml.
Positive Control
1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes
EXOSC4 antibody can be used for detection of EXOSC4 by ELISA at 1:62500. EXOSC4 antibody can be used for detection of EXOSC4 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store EXOSC4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt