Application
Western blot analysis of extract from HepG2, 293, C6, HUVEC and HT29 cells using FAK (Ab-397).| Product Name | FAK Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, PTK2 |
| Product description | Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.1) von Sengbusch A, et al. (2005) Am J Pathol ; 166 (2): 585-596Fornaro M, et al. (2000) Mol Biol Cell ; 11 (7): 2235-2249Zhang X, et al. (1999) Proc Natl Acad Sci U S A; 96 (16): 9021-9026. |
| Immunogen | FAK (Ab-397) antibody was raised against a peptide sequence around aa. 395~399 (D-D-Y-A-E) derived from FAK. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTK2 |
|---|---|
| Alternative Names | FAK FADK FAK1 FRNK PPP1R71 p125FAK pp125FAK PTK2 |
| Molecular Weight(MW) | 125 kDa |
| Tissue Specificity | This antibody detects endogenous levels of total FAK protein. |
| Entrez Gene | 5747 |
|---|---|
| Protein Accession | NP_005598.3 |
Application
Western blot analysis of extract from HepG2, 293, C6, HUVEC and HT29 cells using FAK (Ab-397).| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
