This nuclear gene encodes a mitochondrial protein which
belongs to FRATAXIN family. The protein functions in regulating
mitochondrial iron transport and respiration. The expansion of
intronic trinucleotide repeat GAA results in Friedreich ataxia.
Alternative splicing results in multiple transcript variants.1) Tsai, C.L., et al. Biochemistry 49(43):9132-9139(2010)
Immunogen
This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human FXN.
Western Blot at 1:1000 dilution + CCRF-CEM whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.