Application
Immunohistochemistry staining of FXR2 in cerebellum tissue using FXR2 monoclonal Antibody.| Product Name | FXR2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FXR2, FXR2P, FMR1L2 |
| Product description | Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins. FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. FXR2 associates with polyribosomes, predominantly with 60S large ribosomal subunits. It may self-associate or interact with FMRP and FXR1. FXR2 may have a role in the development of fragile X mental retardation syndrome. |
| Immunogen | FXR2 monoclonal antibody was raised against amino acids 414 - 658 of FXR2 (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| FXR2 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FXR2 |
|---|---|
| Alternative Names | FXR2 FXR2P FMR1L2 |
Application
Immunohistochemistry staining of FXR2 in cerebellum tissue using FXR2 monoclonal Antibody.| Application Notes | FXR2 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | FXR2 antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | Ascites, 0.1% sodium azide. |
