Application
Antibody used in WB on Human Liver at 0.2-1 ug/ml.| Product Name | GCHFR Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.1) Ohta, E., (2006) Arch. Neurol. 63 (11), 1605-1610. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GCHFR. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| GCHFR antibody can be used for detection of GCHFR by ELISA at 1:312500. GCHFR antibody can be used for detection of GCHFR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GCHFR |
|---|---|
| Alternative Names | GCHFR GFRP HsT16933 MGC138467 MGC138469 P35 |
| Molecular Weight(MW) | 10 kDa |
Application
Antibody used in WB on Human Liver at 0.2-1 ug/ml.| Application Notes | GCHFR antibody can be used for detection of GCHFR by ELISA at 1:312500. GCHFR antibody can be used for detection of GCHFR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store GCHFR antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
